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Assay Detail

CHEMBL3266916

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of porcine pancreatic lipase assessed as hydrolysis of p-NPB to p-nitrophenol by microplate reader
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Pancreatic triacylglycerol lipase (CHEMBL1687677)
Type SINGLE PROTEIN
Organism Sus scrofa

Publication

Optimization of pancreatic lipase inhibition by Cudrania tricuspidata fruits using response surface methodology.
Jeong JY, Jo YH, Lee KY, Do SG, Hwang BY, Lee MK.
Bioorg Med Chem Lett (2014) 24 : 2329 -2333
PubMed 24751440 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.19 4.19
Inhibition 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL494252 2 4.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL494252 IC50 = 65000.0 nM 4.19
CHEMBL494252 Inhibition - % -