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Assay Detail

CHEMBL3269733

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of ribonucleotide reductase (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Thienoquinolines as novel disruptors of the PKCε/RACK2 protein-protein interaction.
Rechfeld F, Gruber P, Kirchmair J, Boehler M, Hauser N, Hechenberger G, Garczarczyk D, Lapa GB, Preobrazhenskaya MN, Goekjian P, Langer T, Hofmann J.
J Med Chem (2014) 57 : 3235 -3246
PubMed 24712764 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.43 4.43

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL467 HYDROXYUREA 4.0 1 4.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL467 HYDROXYUREA IC50 = 37200.0 nM 4.43