Assay Detail
Binding
CHEMBL3281102
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of porcine pancreatic kallikrein using BPPANA as substrate after 15 to 180 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel bis(benzamidino) compounds with an aromatic central link. Inhibitors of thrombin, pancreatic kallikrein, trypsin, and complement.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.86 | 7.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL547724 | — | — | 1 | 7.51 |
| CHEMBL3277923 | — | — | 1 | 6.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL547724 | — | Ki | = | 31.0 | nM | 7.51 |
| CHEMBL3277923 | — | Ki | = | 610.0 | nM | 6.21 |