Assay Detail
Binding
CHEMBL3291699
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Binding affinity to Bcl-xL (unknown origin)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Prediction of anti-tumor chemical probes of a traditional Chinese medicine formula by HPLC fingerprinting combined with molecular docking.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 8 | 7.32 | 9.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3121562 | — | — | 1 | 9.90 |
| CHEMBL3289607 | — | — | 1 | 8.62 |
| CHEMBL233929 | GALUTEOLIN | — | 1 | 8.01 |
| CHEMBL487017 | APIGETRIN | — | 1 | 7.12 |
| CHEMBL3289608 | — | — | 1 | 6.96 |
| CHEMBL465980 | ONONIN | — | 1 | 6.77 |
| CHEMBL371861 | — | — | 1 | 6.09 |
| CHEMBL242341 | FORMONONETIN | 2.0 | 1 | 5.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3121562 | — | Kd | = | 0.126 | nM | 9.90 |
| CHEMBL3289607 | — | Kd | = | 2.4 | nM | 8.62 |
| CHEMBL233929 | GALUTEOLIN | Kd | = | 9.89 | nM | 8.01 |
| CHEMBL487017 | APIGETRIN | Kd | = | 76.2 | nM | 7.12 |
| CHEMBL3289608 | — | Kd | = | 110.0 | nM | 6.96 |
| CHEMBL465980 | ONONIN | Kd | = | 170.0 | nM | 6.77 |
| CHEMBL371861 | — | Kd | = | 810.0 | nM | 6.09 |
| CHEMBL242341 | FORMONONETIN | Kd | = | 7750.0 | nM | 5.11 |