Assay Detail
Binding
CHEMBL3294608
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Displacement of [3H]5-HT from 5-HT2C receptor (unknown origin) expressed in hamster AV12 cells
4
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | AV12 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel aza-analogous ergoline derived scaffolds as potent serotonin 5-HT₆ and dopamine D₂ receptor ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.36 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3286580 | IDALOPIRDINE | 3.0 | 2 | 6.60 |
| CHEMBL431298 | — | — | 2 | 6.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3286580 | IDALOPIRDINE | Ki | = | 250.0 | nM | 6.60 |
| CHEMBL3286580 | IDALOPIRDINE | Ki | = | 251.19 | nM | 6.60 |
| CHEMBL431298 | — | Ki | = | 770.0 | nM | 6.11 |
| CHEMBL431298 | — | Ki | = | 776.25 | nM | 6.11 |