Assay Detail
Binding
CHEMBL3294873
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to PDE-delta (unknown origin) by time-resolved fluorescence anisotropic analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (CHEMBL3860) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Structure guided design and kinetic analysis of highly potent benzimidazole inhibitors targeting the PDEδ prenyl binding site.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 7.25 | 8.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3286929 | — | — | 1 | 8.96 |
| CHEMBL1922082 | — | — | 1 | 5.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3286929 | — | Kd | = | 1.1 | nM | 8.96 |
| CHEMBL1922082 | — | Kd | = | 2900.0 | nM | 5.54 |