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Assay Detail

CHEMBL3296467

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Functional
Antimalarial activity against Plasmodium falciparum infected in human erythrocytes after 72 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages.
Hansen FK, Sumanadasa SD, Stenzel K, Duffy S, Meister S, Marek L, Schmetter R, Kuna K, Hamacher A, Mordmüller B, Kassack MU, Winzeler EA, Avery VM, Andrews KT, Kurz T.
Eur J Med Chem (2014) 82 : 204 -213
PubMed 24904967 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.10 7.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1851943 PRACINOSTAT 3.0 1 7.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1851943 PRACINOSTAT IC50 = 80.0 nM 7.10