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Assay Detail

CHEMBL3300064

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Competitive inhibition of GLO1 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Lactoylglutathione lyase (CHEMBL2424)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Inhibition by active site directed covalent modification of human glyoxalase I.
Holewinski RJ, Creighton DJ.
Bioorg Med Chem (2014) 22 : 3301 -3308
PubMed 24856185 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.34 7.34

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL131578 1 7.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL131578 Ki = 46.0 nM 7.34