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Assay Detail

CHEMBL3362270

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at mouse FFA4 receptor in mouse MIN6 cells assessed as induction of glucose-induced insulin secretion by AlphaLISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mus musculus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Free fatty acid receptor 4 (CHEMBL2052036)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
Sparks SM, Chen G, Collins JL, Danger D, Dock ST, Jayawickreme C, Jenkinson S, Laudeman C, Leesnitzer MA, Liang X, Maloney P, McCoy DC, Moncol D, Rash V, Rimele T, Vulimiri P, Way JM, Ross S.
Bioorg Med Chem Lett (2014) 24 : 3100 -3103
PubMed 24881566 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.20 5.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3311308 1 5.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3311308 EC50 = 6309.57 nM 5.20