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Assay Detail

CHEMBL3362653

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antagonist activity at human GABAA alpha3beta3gamma2 receptor by FLIPR/summary (Abse5) assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 7 — Homologous single protein target
Curated By Autocuration

Target

GABA-A receptor; alpha-3/beta-3/gamma-2 (CHEMBL2094120)
Type PROTEIN COMPLEX
Organism Homo sapiens

Publication

Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
Sparks SM, Chen G, Collins JL, Danger D, Dock ST, Jayawickreme C, Jenkinson S, Laudeman C, Leesnitzer MA, Liang X, Maloney P, McCoy DC, Moncol D, Rash V, Rimele T, Vulimiri P, Way JM, Ross S.
Bioorg Med Chem Lett (2014) 24 : 3100 -3103
PubMed 24881566 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.50 4.50

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3311308 1 4.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3311308 IC50 = 31622.78 nM 4.50