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Assay Detail

CHEMBL3363805

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rabbit erythrocyte S-adenosylhomocysteine hydrolase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

The enantiomers of the 1',6'-isomer of neplanocin A: synthesis and antiviral properties.
Ye W, Schneller SW.
Bioorg Med Chem (2014) 22 : 5315 -5319
PubMed 25155914 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 8.56 9.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3334763 1 9.05
CHEMBL8771 NEOPLANOCIN A 1 9.05
CHEMBL3334764 1 7.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3334763 IC50 = 0.9 nM 9.05
CHEMBL8771 NEOPLANOCIN A IC50 = 0.9 nM 9.05
CHEMBL3334764 IC50 = 27.0 nM 7.57