Assay Detail
Functional
CHEMBL3363807
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Antiviral activity against Hepatitis B virus infected in HepG2.2.15 cells assessed as inhibition of viral-induced cytopathicity
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Hepatitis B virus |
| Cell Type | HepG2 2.2.15 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The enantiomers of the 1',6'-isomer of neplanocin A: synthesis and antiviral properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.14 | 5.14 |
| EC90 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3334763 | — | — | 2 | 5.14 |
| CHEMBL3334764 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3334763 | — | EC50 | = | 7200.0 | nM | 5.14 |
| CHEMBL3334764 | — | EC50 | - | — | - | |
| CHEMBL3334763 | — | EC90 | = | 35.0 | uM | - |