Assay Detail
Binding
CHEMBL3364116
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human NTPDase2 transfected in COS-7 cells using ATP substrate
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | COS-7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Ectonucleoside triphosphate diphosphohydrolase 2 (CHEMBL5049) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
2-Hexylthio-β,γ-CH2-ATP is an effective and selective NTPDase2 inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 4.68 | 4.68 |
| IC50 | 1 | 4.40 | 4.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3314932 | — | — | 2 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3314932 | — | Ki | = | 21000.0 | nM | 4.68 |
| CHEMBL3314932 | — | IC50 | = | 40000.0 | nM | 4.40 |