Assay Detail
Binding
CHEMBL3364246
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Inhbition of Influenza A virus (A/X-31(H3N2) hemagglutinin binding to 2 hrs compound pre-incubated MDCK cells assessed as reduction in viral RNA measured after 1 hr by RT-qPCR analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Influenza A virus (A/X-31(H3N2)) |
| Cell Type | MDCK |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Semisynthetic teicoplanin derivatives as new influenza virus binding inhibitors: synthesis and antiviral studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.25 | 5.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3310642 | — | — | 1 | 5.33 |
| CHEMBL3310643 | — | — | 1 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3310642 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL3310643 | — | IC50 | = | 7000.0 | nM | 5.16 |