Assay Detail
Functional
CHEMBL3364310
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Antiparasitic activity against Cryptosporidium hominis Iowa intracellular forms infected in human HCT8 cells assessed as reduction in parasite infection dosed 2 hrs after parasite infection
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cryptosporidium hominis |
| Cell Type | HCT-8 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2426247 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2426247 | — | EC50 | = | 1000.0 | nM | 6.00 |