Assay Detail
Binding
CHEMBL3364447
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometry relative to control
5
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Effect of p-aminophenols on tyrosinase activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.50 | 4.52 |
| Inhibition | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL427462 | — | — | 2 | 4.52 |
| CHEMBL287556 | KOJIC ACID | — | 1 | 4.48 |
| CHEMBL376316 | — | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL427462 | — | IC50 | = | 30100.0 | nM | 4.52 |
| CHEMBL287556 | KOJIC ACID | IC50 | = | 32800.0 | nM | 4.48 |
| CHEMBL376316 | — | IC50 | > | 200000.0 | nM | - |
| CHEMBL376316 | — | Inhibition | - | % | - | |
| CHEMBL427462 | — | Inhibition | - | % | - |