Assay Detail
Binding
CHEMBL3364478
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Inhibition of FPPS (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Biased and unbiased strategies to identify biologically active small molecules.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.90 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3314098 | — | — | 1 | 7.10 |
| CHEMBL1231307 | — | — | 1 | 6.70 |
| CHEMBL1230159 | — | — | 1 | - |
| CHEMBL1230158 | TIANAFAC | 2.0 | 1 | - |
| CHEMBL1230160 | — | — | 1 | - |
| CHEMBL1234470 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3314098 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL1231307 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL1230159 | — | IC50 | > | 500000000.0 | nM | - |
| CHEMBL1230158 | TIANAFAC | IC50 | > | 500000000.0 | nM | - |
| CHEMBL1230160 | — | IC50 | > | 500000000.0 | nM | - |
| CHEMBL1234470 | — | IC50 | > | 500000000.0 | nM | - |