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Assay Detail

CHEMBL3364895

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity at mouse FFA4 receptor expressed in U2OS cells assessed as calcium mobilization after 24 hrs by FLIPR
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type U2OS
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Free fatty acid receptor 4 (CHEMBL2052036)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120).
Sparks SM, Chen G, Collins JL, Danger D, Dock ST, Jayawickreme C, Jenkinson S, Laudeman C, Leesnitzer MA, Liang X, Maloney P, McCoy DC, Moncol D, Rash V, Rimele T, Vulimiri P, Way JM, Ross S.
Bioorg Med Chem Lett (2014) 24 : 3100 -3103
PubMed 24881566 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.20 6.20

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3311308 1 6.20

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3311308 EC50 = 630.96 nM 6.20