Assay Detail
Binding
CHEMBL3365235
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Partial agonist activity at alpha7 nAChR (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Neuronal acetylcholine receptor subunit alpha-7 (CHEMBL2492) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.82 | 6.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3341967 | — | — | 1 | 6.40 |
| CHEMBL497939 | CYTISINICLINE | 3.0 | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3341967 | — | Ki | = | 399.0 | nM | 6.40 |
| CHEMBL497939 | CYTISINICLINE | Ki | = | 5890.0 | nM | 5.23 |