Assay Detail
Binding
CHEMBL3365238
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Binding affinity to alpha7* nAChR (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Recent developments in novel antidepressants targeting α4β2-nicotinic acetylcholine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.76 | 7.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3358447 | — | — | 1 | 7.55 |
| CHEMBL3341963 | — | — | 1 | 5.96 |
| CHEMBL188462 | ISPRONICLINE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3358447 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL3341963 | — | Ki | = | 1100.0 | nM | 5.96 |
| CHEMBL188462 | ISPRONICLINE | Ki | > | 50000.0 | nM | - |