Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL3365335

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiamoebic activity against Entamoeba histolytica
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Entamoeba histolytica
Confidence 1 — Organism
Curated By Autocuration

Target

Entamoeba histolytica (CHEMBL612853)
Type ORGANISM
Organism Entamoeba histolytica

Publication

Present status of quinoxaline motifs: excellent pathfinders in therapeutic medicine.
Ajani OO.
Eur J Med Chem (2014) 85 : 688 -715
PubMed 25128670 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.94 7.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL489483 1 7.10
CHEMBL491969 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL489483 IC50 = 80.0 nM 7.10
CHEMBL491969 IC50 = 170.0 nM 6.77