Assay Detail
Functional
CHEMBL3365530
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human MCF7 cells assessed as cell viability after 72 hrs by CCK cell proliferation assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Total syntheses of parthenolide and its analogues with macrocyclic stereocontrol.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.01 | 5.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL477923 | — | — | 1 | 5.23 |
| CHEMBL4298697 | — | — | 1 | 5.16 |
| CHEMBL3322516 | — | — | 1 | 4.89 |
| CHEMBL3322515 | — | — | 1 | 4.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL477923 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL4298697 | — | IC50 | = | 6900.0 | nM | 5.16 |
| CHEMBL3322516 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL3322515 | — | IC50 | = | 17600.0 | nM | 4.75 |