Assay Detail
Binding
CHEMBL3365678
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Binding affinity to CK2alpha (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis of novel chiral TBBt derivatives with hydroxyl moiety. Studies on inhibition of human protein kinase CK2α and cytotoxicity properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.90 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL376505 | — | — | 1 | 7.40 |
| CHEMBL177820 | TETRABROMOBENZOTRIAZOLE | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL376505 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL177820 | TETRABROMOBENZOTRIAZOLE | Ki | = | 400.0 | nM | 6.40 |