Assay Detail
Functional
CHEMBL3366896
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Antiplasmodium activity against blood stage Plasmodium falciparum 3D7
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasites.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.34 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL591637 | — | — | 1 | 6.70 |
| CHEMBL470514 | — | — | 1 | 6.46 |
| CHEMBL591362 | — | — | 1 | 5.87 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL591637 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL470514 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL591362 | — | IC50 | = | 1360.0 | nM | 5.87 |