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Assay Detail

CHEMBL3367270

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Binding
Inhibition of xanthine oxidase (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Xanthine dehydrogenase/oxidase (CHEMBL1929)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Flavones: an important scaffold for medicinal chemistry.
Singh M, Kaur M, Silakari O.
Eur J Med Chem (2014) 84 : 206 -239
PubMed 25019478 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 5.65 6.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL28 APIGENIN 1 6.28
CHEMBL151 LUTEOLIN 2.0 1 5.54
CHEMBL1467 ALLOPURINOL 4.0 1 5.14

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL28 APIGENIN Ki = 520.0 nM 6.28
CHEMBL151 LUTEOLIN Ki = 2900.0 nM 5.54
CHEMBL1467 ALLOPURINOL Ki = 7300.0 nM 5.14