Assay Detail
Functional
CHEMBL3367768
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Antimicrobial activity against amastigote stage of Leishmania infantum
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania infantum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, antileishmanial and antitrypanosomal activities of N-substituted tetrahydro-β-carbolines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.38 | 6.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL269538 | HARMINE | 1.0 | 1 | 6.64 |
| CHEMBL12014 | HARMAN | — | 1 | 6.57 |
| CHEMBL340807 | HARMALINE | — | 1 | 5.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL269538 | HARMINE | IC50 | = | 230.0 | nM | 6.64 |
| CHEMBL12014 | HARMAN | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL340807 | HARMALINE | IC50 | = | 1160.0 | nM | 5.94 |