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Assay Detail

CHEMBL3367778

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against pig LLC-PK1 cells after 48 hrs by neutral red assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Sus scrofa
Cell Type LLC-PK1
Confidence 1 — Organism
Curated By Autocuration

Target

LLC-PK1 (CHEMBL614577)
Type CELL-LINE
Organism Sus scrofa

Publication

Synthesis, antileishmanial and antitrypanosomal activities of N-substituted tetrahydro-β-carbolines.
Manda S, Khan SI, Jain SK, Mohammed S, Tekwani BL, Khan IA, Vishwakarma RA, Bharate SB.
Bioorg Med Chem Lett (2014) 24 : 3247 -3250
PubMed 24980054 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.25 4.25

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3309533 1 4.25

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3309533 IC50 = 56000.0 nM 4.25