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Assay Detail

CHEMBL3368168

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of DNase 1 (unknown origin) using (FAM)-labeled dsDNA as substrate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Deoxyribonuclease-1 (CHEMBL3351219)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Deoxyribonuclease inhibitors.
Kolarevic A, Yancheva D, Kocic G, Smelcerovic A.
Eur J Med Chem (2014) 88 : 101 -111
PubMed 25042005 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.46 6.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL64894 GENTIAN VIOLET 4.0 1 6.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL64894 GENTIAN VIOLET IC50 = 350.0 nM 6.46