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Assay Detail

CHEMBL3368209

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human recombinant IDO using L-tryptophan as substrate
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Indoleamine 2,3-dioxygenase 1 (CHEMBL4685)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors.
Cheng MF, Hung MS, Song JS, Lin SY, Liao FY, Wu MH, Hsiao W, Hsieh CL, Wu JS, Chao YS, Shih C, Wu SY, Ueng SH.
Bioorg Med Chem Lett (2014) 24 : 3403 -3406
PubMed 24939758 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 4.47 4.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL513172 1-METHYLTRYPTOPHAN 1 4.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL513172 1-METHYLTRYPTOPHAN Ki = 34000.0 nM 4.47