Assay Detail
Binding
CHEMBL3368935
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Binding affinity to RORc-LBD (unknown origin) by radioligand binding assay
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Modulators of the nuclear receptor retinoic acid receptor-related orphan receptor-γ (RORγ or RORc).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.00 | 6.00 |
| Ki | 1 | 6.96 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3094388 | — | — | 1 | 6.96 |
| CHEMBL3218917 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3094388 | — | Ki | = | 111.0 | nM | 6.96 |
| CHEMBL3218917 | — | IC50 | = | 1000.0 | nM | 6.00 |