Assay Detail
Binding
CHEMBL3370548
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of porcine gastric mucosa pepsin using MOCAc-Ala-Pro-Ala-Lys-Phe-Phe-Arg-Leu-Lys (Dnp)-NH2 as substrate after 20 mins by fluorescence assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Tissue | Gastric mucosa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Lower homologues of ahpatinin, aspartic protease inhibitors, from a marine Streptomyces sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 7.74 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301728 | ACETYLPEPSTATIN | — | 1 | 7.96 |
| CHEMBL3314607 | — | — | 1 | 7.96 |
| CHEMBL3314610 | — | — | 1 | 7.75 |
| CHEMBL3314608 | — | — | 1 | 7.30 |
| CHEMBL3314609 | — | — | 1 | - |
| CHEMBL3314611 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301728 | ACETYLPEPSTATIN | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL3314607 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL3314610 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL3314608 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL3314609 | — | IC50 | - | — | - | |
| CHEMBL3314611 | — | IC50 | - | — | - |