Assay Detail
Binding
CHEMBL3371805
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at GAL4-tagged PPARgamma (unknown origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Biological evaluation and structural insights for design of subtype-selective peroxisome proliferator activated receptor-α (PPAR-α) agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 5.86 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL435523 | — | — | 1 | 8.22 |
| CHEMBL247951 | PEMAFIBRATE | 4.0 | 1 | 5.77 |
| CHEMBL1934484 | — | — | 1 | 5.51 |
| CHEMBL1934476 | — | — | 1 | 5.18 |
| CHEMBL3354989 | — | — | 1 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL435523 | — | EC50 | = | 6.0 | nM | 8.22 |
| CHEMBL247951 | PEMAFIBRATE | EC50 | = | 1700.0 | nM | 5.77 |
| CHEMBL1934484 | — | EC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL1934476 | — | EC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL3354989 | — | EC50 | = | 25000.0 | nM | 4.60 |