Assay Detail
ADMET
CHEMBL3371863
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Reduction in peripheral lymphocyte count in orally dosed monkey measured after 24 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Macaca mulatta |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.01 | 7.01 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3358920 | ETRASIMOD | 4.0 | 1 | 7.01 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3358920 | ETRASIMOD | IC50 | = | 98.0 | nM | 7.01 |