Assay Detail

CHEMBL3373362

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Agonist activity at goat NK3R

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Capra hircus
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation.

Misu R, Oishi S, Yamada A, Yamamura T, Matsuda F, Yamamoto K, Noguchi T, Ohno H, Okamura H, Ohkura S, Fujii N.
J Med Chem (2014) 57 : 8646 -8651
PubMed 25247671 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	2	7.94	7.96

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL3361404	—	—	1	7.96
CHEMBL106124	SENKTIDE	—	1	7.92

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL3361404	—	EC50	=	11.0	nM	7.96
CHEMBL106124	SENKTIDE	EC50	=	12.0	nM	7.92