Assay Detail
Binding
CHEMBL3373728
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PIM1 (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase pim-1 (CHEMBL2147) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Pim kinase inhibitors for the treatment of cancer and possibly more.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 10.58 | 11.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3318854 | — | — | 1 | 11.00 |
| CHEMBL3318856 | — | — | 1 | 10.15 |
| CHEMBL3318853 | — | — | 1 | - |
| CHEMBL3318855 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3318854 | — | Ki | = | 0.01 | nM | 11.00 |
| CHEMBL3318856 | — | Ki | = | 0.071 | nM | 10.15 |
| CHEMBL3318853 | — | Ki | = | 0.006 | nM | - |
| CHEMBL3318855 | — | Ki | = | 0.003 | nM | - |