Assay Detail
Binding
CHEMBL3375708
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Streptococcus pneumoniae diphosphomevalonate decarboxylase assessed as conversion of (R)-5-diphosphomevalonate to ADP by fluorometry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Streptococcus pneumoniae |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.62 | 4.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1570441 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1570441 | — | IC50 | = | 24000.0 | nM | 4.62 |