Assay Detail
Functional
CHEMBL3375737
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Cytotoxicity against human HeLa cells after 24 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Melleolides induce rapid cell death in human primary monocytes and cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 5.17 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1762770 | DEHYDROARMILLYLORSELLINATE | — | 1 | 5.80 |
| CHEMBL1078389 | ARNAMIAL | — | 1 | 5.31 |
| CHEMBL1762764 | ARMILLARIDIN | — | 1 | 5.04 |
| CHEMBL3311029 | — | — | 1 | 4.91 |
| CHEMBL1762773 | ARMILLARIN | — | 1 | 4.78 |
| CHEMBL1078142 | MELLEOLIDE D | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1762770 | DEHYDROARMILLYLORSELLINATE | EC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL1078389 | ARNAMIAL | EC50 | = | 4900.0 | nM | 5.31 |
| CHEMBL1762764 | ARMILLARIDIN | EC50 | = | 9200.0 | nM | 5.04 |
| CHEMBL3311029 | — | EC50 | = | 12300.0 | nM | 4.91 |
| CHEMBL1762773 | ARMILLARIN | EC50 | = | 16700.0 | nM | 4.78 |
| CHEMBL1078142 | MELLEOLIDE D | EC50 | > | 100000.0 | nM | - |