Assay Detail
Functional
CHEMBL3376590
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Cytotoxicity against human A549 cells by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Nannozinones and sorazinones, unprecedented pyrazinones from myxobacteria.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.99 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL303290 | — | — | 1 | 6.92 |
| CHEMBL3355651 | — | — | 1 | 5.06 |
| CHEMBL3355650 | — | — | 1 | - |
| CHEMBL2270066 | — | — | 1 | - |
| CHEMBL3355652 | — | — | 1 | - |
| CHEMBL443794 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL303290 | — | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL3355651 | — | IC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL3355650 | — | IC50 | > | 41500.0 | nM | - |
| CHEMBL2270066 | — | IC50 | > | 56800.0 | nM | - |
| CHEMBL3355652 | — | IC50 | > | 50000.0 | nM | - |
| CHEMBL443794 | — | IC50 | > | 34500.0 | nM | - |