Assay Detail
Binding
CHEMBL3376605
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Inhibition of Escherichia coli TrmD
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Trends and exceptions of physical properties on antibacterial activity for Gram-positive and Gram-negative pathogens.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.74 | 6.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2432017 | — | — | 1 | 6.54 |
| CHEMBL3355658 | — | — | 1 | 5.92 |
| CHEMBL1369722 | — | — | 1 | 4.77 |
| CHEMBL3355659 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2432017 | — | IC50 | = | 290.0 | nM | 6.54 |
| CHEMBL3355658 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL1369722 | — | IC50 | = | 17000.0 | nM | 4.77 |
| CHEMBL3355659 | — | IC50 | < | 0.5 | nM | - |