Assay Detail
Binding
CHEMBL3377246
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Inhibition of DLK (unknown origin) by RT-FRET assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Dual leucine zipper kinase inhibitors: potential treatments for neurodegenerative diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.18 | 9.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3355003 | — | — | 1 | 9.77 |
| CHEMBL3355005 | — | — | 1 | 9.40 |
| CHEMBL3355004 | — | — | 1 | 6.96 |
| CHEMBL3355006 | — | — | 1 | 6.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3355003 | — | Ki | = | 0.17 | nM | 9.77 |
| CHEMBL3355005 | — | Ki | = | 0.4 | nM | 9.40 |
| CHEMBL3355004 | — | Ki | = | 110.0 | nM | 6.96 |
| CHEMBL3355006 | — | Ki | = | 270.0 | nM | 6.57 |