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Assay Detail

CHEMBL3377317

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human A549 cells by SRB assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type A549
Confidence 1 — Organism
Curated By Autocuration

Target

A549 (CHEMBL392)
Type CELL-LINE
Organism Homo sapiens

Publication

Bioactive constituents from the green alga Caulerpa racemosa.
Yang P, Liu DQ, Liang TJ, Li J, Zhang HY, Liu AH, Guo YW, Mao SC.
Bioorg Med Chem (2015) 23 : 38 -45
PubMed 25497963 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 11 5.23 6.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL53463 DOXORUBICIN 4.0 1 6.38
CHEMBL1223852 1 4.07
CHEMBL3356396 1 -
CHEMBL1644111 TRANS-PHYTOL 1 -
CHEMBL3356397 1 -
CHEMBL3356398 1 -
CHEMBL3356399 1 -
CHEMBL524098 1 -
CHEMBL489548 1 -
CHEMBL3356400 1 -
CHEMBL2204408 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL53463 DOXORUBICIN IC50 = 414.0 nM 6.38
CHEMBL1223852 IC50 = 85300.0 nM 4.07
CHEMBL3356396 IC50 > 100000.0 nM -
CHEMBL1644111 TRANS-PHYTOL IC50 > 100000.0 nM -
CHEMBL3356397 IC50 > 100000.0 nM -
CHEMBL3356398 IC50 > 100000.0 nM -
CHEMBL3356399 IC50 > 100000.0 nM -
CHEMBL524098 IC50 > 100000.0 nM -
CHEMBL489548 IC50 > 100000.0 nM -
CHEMBL3356400 IC50 > 100000.0 nM -
CHEMBL2204408 IC50 > 100000.0 nM -