Assay Detail
Binding
CHEMBL3377958
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of RAD1 (unknown origin) binding to ssDNA
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Cell cycle checkpoint protein RAD1 (CHEMBL3309116) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting the homologous recombination pathway by small molecule modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 5.06 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1162148 | — | — | 1 | 6.00 |
| CHEMBL1271993 | — | — | 1 | 5.30 |
| CHEMBL1567670 | — | — | 1 | 4.57 |
| CHEMBL2316726 | — | — | 1 | 4.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1162148 | — | EC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL1271993 | — | EC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL1567670 | — | EC50 | = | 27000.0 | nM | 4.57 |
| CHEMBL2316726 | — | EC50 | = | 44000.0 | nM | 4.36 |