Assay Detail
Binding
CHEMBL3377959
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to RAD1 (unknown origin) by surface plasmon resonance method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Cell cycle checkpoint protein RAD1 (CHEMBL3309116) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting the homologous recombination pathway by small molecule modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 5.48 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1162148 | — | — | 1 | 5.70 |
| CHEMBL1567670 | — | — | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1162148 | — | Kd | = | 2000.0 | nM | 5.70 |
| CHEMBL1567670 | — | Kd | = | 5600.0 | nM | 5.25 |