Assay Detail
Binding
CHEMBL3377968
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of RAD54 (unknown origin) ATPase activity assessed as generation of reactive oxygen species
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
DNA repair and recombination protein RAD54-like (CHEMBL2146297) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Targeting the homologous recombination pathway by small molecule modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.78 | 4.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL11417 | STREPTONIGRIN | 2.0 | 1 | 4.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL11417 | STREPTONIGRIN | EC50 | = | 16500.0 | nM | 4.78 |