Assay Detail
Binding
CHEMBL3378174
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Inhibition of glycogen phosphorylase b (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure based inhibitor design targeting glycogen phosphorylase B. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylamines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.80 | 8.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3322297 | — | — | 1 | 8.80 |
| CHEMBL3322298 | — | — | 1 | - |
| CHEMBL423707 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3322297 | — | Ki | = | 1.6 | nM | 8.80 |
| CHEMBL3322298 | — | Ki | = | 1000000.0 | nM | - |
| CHEMBL423707 | — | Ki | = | 1700000.0 | nM | - |