Assay Detail
Binding
CHEMBL3378641
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]SS-14 from mouse SSTR3 expressed in CHO cells by TopCount analyzer
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 16 | 9.02 | 9.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3323072 | — | — | 1 | 9.39 |
| CHEMBL3323074 | — | — | 1 | 9.39 |
| CHEMBL3323073 | — | — | 1 | 9.15 |
| CHEMBL3323082 | — | — | 1 | 8.76 |
| CHEMBL3323080 | — | — | 1 | 8.41 |
| CHEMBL3323075 | — | — | 1 | - |
| CHEMBL3323076 | — | — | 1 | - |
| CHEMBL3323077 | — | — | 1 | - |
| CHEMBL3323078 | — | — | 1 | - |
| CHEMBL3323079 | — | — | 1 | - |
| CHEMBL3323081 | — | — | 1 | - |
| CHEMBL3323083 | — | — | 1 | - |
| CHEMBL3323084 | — | — | 1 | - |
| CHEMBL3323085 | — | — | 1 | - |
| CHEMBL3323086 | — | — | 1 | - |
| CHEMBL3323087 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3323072 | — | IC50 | = | 0.41 | nM | 9.39 |
| CHEMBL3323074 | — | IC50 | = | 0.41 | nM | 9.39 |
| CHEMBL3323073 | — | IC50 | = | 0.7 | nM | 9.15 |
| CHEMBL3323082 | — | IC50 | = | 1.72 | nM | 8.76 |
| CHEMBL3323080 | — | IC50 | = | 3.93 | nM | 8.41 |
| CHEMBL3323075 | — | IC50 | - | — | - | |
| CHEMBL3323076 | — | IC50 | - | — | - | |
| CHEMBL3323077 | — | IC50 | - | — | - | |
| CHEMBL3323078 | — | IC50 | - | — | - | |
| CHEMBL3323079 | — | IC50 | - | — | - | |
| CHEMBL3323081 | — | IC50 | - | — | - | |
| CHEMBL3323083 | — | IC50 | - | — | - | |
| CHEMBL3323084 | — | IC50 | - | — | - | |
| CHEMBL3323085 | — | IC50 | - | — | - | |
| CHEMBL3323086 | — | IC50 | - | — | - | |
| CHEMBL3323087 | — | IC50 | - | — | - |