Assay Detail
Functional
CHEMBL3379459
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of biofilm formation of Candida albicans SC5314 incubated for 48 hrs by XTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Candida albicans |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Polyketide glycosides from Bionectria ochroleuca inhibit Candida albicans biofilm formation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.72 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3344123 | — | — | 1 | 5.96 |
| CHEMBL3344126 | — | — | 1 | 5.92 |
| CHEMBL3344128 | — | — | 1 | 5.82 |
| CHEMBL3344125 | — | — | 1 | 5.82 |
| CHEMBL3344124 | — | — | 1 | 5.82 |
| CHEMBL3344129 | — | — | 1 | 5.62 |
| CHEMBL458328 | — | — | 1 | 5.47 |
| CHEMBL3344127 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3344123 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL3344126 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL3344128 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL3344125 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL3344124 | — | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL3344129 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL458328 | — | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL3344127 | — | IC50 | = | 5000.0 | nM | 5.30 |