Assay Detail
Binding
CHEMBL3379946
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at adrenergic beta1 receptor in guinea-pig left atria assessed as inhibition of electrically-stimulated contraction
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The identification of 7-[(R)-2-((1S,2S)-2-benzyloxycyclopentylamino)-1-hydroxyethyl]-4-hydroxybenzothiazolone as an inhaled long-acting β2-adrenoceptor agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.56 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1221681 | — | — | 1 | 5.66 |
| CHEMBL1095777 | INDACATEROL | 4.0 | 1 | 5.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1221681 | — | EC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL1095777 | INDACATEROL | EC50 | = | 3500.0 | nM | 5.46 |