Assay Detail
Functional
CHEMBL3380082
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Cytotoxicity against human A549 cells assessed as reduction in cell number
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A549 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic bibenzyl dimers from the stems of Dendrobium fimbriatum Hook.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.92 | 5.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL374047 | MOSCATILIN | — | 1 | 5.24 |
| CHEMBL3337991 | — | — | 1 | 5.18 |
| CHEMBL3337988 | — | — | 1 | 4.84 |
| CHEMBL3337986 | — | — | 1 | 4.81 |
| CHEMBL3337985 | — | — | 1 | 4.79 |
| CHEMBL3337990 | — | — | 1 | 4.78 |
| CHEMBL3337989 | — | — | 1 | 4.78 |
| CHEMBL3337987 | — | — | 1 | - |
| CHEMBL3337992 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL374047 | MOSCATILIN | IC50 | = | 5730.0 | nM | 5.24 |
| CHEMBL3337991 | — | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL3337988 | — | IC50 | = | 14490.0 | nM | 4.84 |
| CHEMBL3337986 | — | IC50 | = | 15550.0 | nM | 4.81 |
| CHEMBL3337985 | — | IC50 | = | 16340.0 | nM | 4.79 |
| CHEMBL3337990 | — | IC50 | = | 16490.0 | nM | 4.78 |
| CHEMBL3337989 | — | IC50 | = | 16640.0 | nM | 4.78 |
| CHEMBL3337987 | — | IC50 | > | 40000.0 | nM | - |
| CHEMBL3337992 | — | IC50 | > | 40000.0 | nM | - |