Assay Detail
Functional
CHEMBL3380083
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Cytotoxicity against human MCF7 cells assessed as reduction in cell number
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic bibenzyl dimers from the stems of Dendrobium fimbriatum Hook.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.91 | 5.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3337988 | — | — | 1 | 5.23 |
| CHEMBL374047 | MOSCATILIN | — | 1 | 5.21 |
| CHEMBL3337990 | — | — | 1 | 5.11 |
| CHEMBL3337986 | — | — | 1 | 4.92 |
| CHEMBL3337991 | — | — | 1 | 4.91 |
| CHEMBL3337985 | — | — | 1 | 4.90 |
| CHEMBL3337989 | — | — | 1 | 4.86 |
| CHEMBL3337987 | — | — | 1 | 4.61 |
| CHEMBL3337992 | — | — | 1 | 4.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3337988 | — | IC50 | = | 5850.0 | nM | 5.23 |
| CHEMBL374047 | MOSCATILIN | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL3337990 | — | IC50 | = | 7750.0 | nM | 5.11 |
| CHEMBL3337986 | — | IC50 | = | 12060.0 | nM | 4.92 |
| CHEMBL3337991 | — | IC50 | = | 12270.0 | nM | 4.91 |
| CHEMBL3337985 | — | IC50 | = | 12670.0 | nM | 4.90 |
| CHEMBL3337989 | — | IC50 | = | 13670.0 | nM | 4.86 |
| CHEMBL3337987 | — | IC50 | = | 24840.0 | nM | 4.61 |
| CHEMBL3337992 | — | IC50 | = | 37120.0 | nM | 4.43 |